Hello arch123. Yes you can. However, more often than not it is suggested not to drink alcohol while taking an antibiotic as it will weaken the potency/effectiveness of the drug. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Fowler on can you drink alcohol while taking ciprofloxacin: All antibiotics in the. Yes, you can drink alcohol while taking Cipro. There are a number of drugs that you should not mix with Cipro, which the Mayo article about the drug spells out at length. There are a number of things that can cause an adverse reaction to Cipro, and one of these substances is alcohol. Not everyone will develop a problem when these two items are mixed; however, it should be avoided if possible so the medication can provide maximum effectiveness. If you were to have a single drink eight hours after your ciprofloxacin dose (and many hours before your next dose), it will probably be fine. But if possible, it's best to avoid alcohol completely when taking antibiotics. While the physical side effects of mixing ciprofloxacin and alcohol may be relatively minor, it is important to consider the negative impact that alcohol has one your immune system as you are taking the antibiotics to assist your immune system in fighting the infection. Are you interested in knowing whether you should take Ciprofloxacin and Alcohol together? It’s a good question that anyone taking Cipro, the brand name of Ciprofloxacin might want to know. Check with your GP or pharmacist when you're given your prescription if you're unsure about whether or not you can drink alcohol while you're taking antibiotics. You can also phone NHS 111 for advice. Alcohol can often lead to dehydration, which will increase the risk of developing these small stones, so it's probably best to avoid alcohol while taking this medication.